PIKIÄ®

PIKIÄ®¹ is a proprietary micro-molecular vegan collagen² developed through a molecular design philosophy³. PIKIÄ possesses an amino acid sequence 100% identical to the collagen found in human skin⁴. These ultra-fine molecules penetrate throughout the stratum corneum, allowing for seamless affinity with the skin. Born from AI-driven design and precision fermentation, PIKIÄ®¹ offers a transformative skincare experience. MIROS is the first in Japan⁵ to formulate with PIKIÄ®, a breakthrough ingredient trusted by the world’s most prestigious luxury spas.

1 sh-Polypeptide-47 (Skin-conditioning agent)

2 Compared to common animal-derived collagens.

3 A development philosophy that analyzes the molecular composition of substances at the nano-level to derive insights.

4 Refers to the identical sequence of Type I collagen.

5 As of December 2025, according to Cambrium researc

PIKIÄ® The Architect of Beauty 

PIKIÄ®¹ is a proprietary micro-molecular vegan collagen² developed through a molecular design philosophy³. PIKIÄ possesses an amino acid sequence 100% identical to the collagen found in human skin⁴. These ultra-fine molecules penetrate throughout the stratum corneum, allowing for seamless affinity with the skin. Born from AI-driven design and precision fermentation, PIKIÄ®¹offers a transformative skincare experience. MIROS is the first in Japan⁵ to formulate with PIKIÄ®, a breakthrough ingredient trusted by the world’s most prestigious luxury spas.

1 sh-Polypeptide-47 (Skin-conditioning agent)

2 Compared to common animal-derived collagens.

3 A development philosophy that analyzes the molecular composition of substances at the nano-level to derive insights.

4 Refers to the identical sequence of Type I collagen.

5 As of December 2025, according to Cambrium research.

AI Design

Through a molecular design approach, vast protein sequence data from nature is analyzed using AI to engineer precise molecular structures. Key performance functions are defined upfront, and candidates are screened through iterative simulations — enabling material innovation driven by efficacy and scalability, not chance.

Precision Fermentation

Guided by insights derived from AI design, fermentation conditions are precisely controlled to minimize molecular variability. This manufacturing technology enables the continuous production of materials defined by uniformity, stability, and uncompromising quality.

3 Key Characteristics

100% Skin-identical
PIKIÄ® features an amino acid sequence that is a 100% match to human skin collagen. Its ultra-high purity and consistency support exceptional formulation freedom.
Precision Micro-Molecules
Our micro-molecular design prioritizes uniform molecular structure and high-precision engineering. With a strong focus on material integrity, we have pursued a structure that ensures a smooth, seamless application while providing the flexibility needed for advanced formulation design.
100% Vegan
A next-generation material developed through precision fermentation without any animal-derived ingredients. It embodies a philosophy of harmony between people and the environment, prioritizing ethics and sustainability.

The Genesis: A Chance Meeting in New York

Headquartered in Germany, Cambrium develops next-generation materials using synthetic biology and AI-driven molecular imaging techniques. The company is backed by leading global investors, including Google’s AI-focused venture arm, and focuses on computational approaches to building bio-based materials.

A chance meeting in New York between Cambrium’s CEO, Mitchell Duffy, and MIROS founder Eita Nakagawa became the spark that led to the creation of MIROS and laid the foundation for its molecular design approach.

Mitchell Duffy (right), CEO of Cambrium

Eita Nakagawa (left), Founder of MIROS

BERLIN, GERMANY – OCT 2025

CONVERSATION

Eita - The cycles of regeneration inherent in the natural world have always been my primary source of inspiration. I am deeply grateful that my curiosity for science and my profound respect for nature have led me to collaborate with the world’s leading biotechnology team.


Mitchell - At Cambrium we use AI to design and build novel proteins.



We’re creating a new material world using nature’s building blocks. 

We began by reimagining one of the most ancient and abundant proteins: collagen.

Eita - In skincare, collagen is essential. It gives our skin a youthful impression.



When I heard Cambrium designed a collagen identical to our own skin, I was instantly drawn in.


Mitchell - We built Cambrium to reimagine and transform industries, beginning with skincare.

Through MIROS, Eita is bringing this holistic vision to life.

Eita - I was inspired by timeless Japanese principles.

But what fascinates me is how this technology can unite something so deeply rooted in tradition, with the materials of the future.

Mitchell - Focusing on collagen—the most abundant protein in the extracellular matrix—we have successfully leveraged AI to decode the blueprints of molecular evolution spanning millions of years. Guided by these blueprints and powered by precision fermentation, we have created a 100% vegan, nano-sized collagen that possesses a sequence identical to that of human skin. This unique collagen has the power to restore and optimize the skin’s inherent condition.