PIKIÄ®¹ is a proprietary micro-molecular vegan collagen² developed through frontier biotechnology research. By using AI to analyze vast amounts of protein data found in nature, we engineered a molecular structure designed for high compatibility with human skin. PIKIÄ® has an amino acid sequence 100% identical to the collagen naturally found in skin².
These ultra-fine collagen peptides are absorbed seamlessly throughout the skin as though syncing with its natural rhythm. Trusted by luxury spas around the world, MIROS is the first brand in Japan to formulate with PIKIÄ®³.
*1 sh-Polypeptide-47 (Skin-conditioning agent)
*2 Based on the physical characteristics of a cosmetic ingredient
*3 Based on the ingredient supply agreement between Sancta Inc. and Cambrium GmbH (Germany), the manufacturer of PIKIÄ® (as of Januar y 2026). PIKIÄ® is formulated in cosmetics in Japan for the first time in the four MIROS skincare products: Hydrating Treatment Lotion, Infusion Emulsion, Serum 8, and Radiance Cream.
Proprietary Collagen PIKIÄ®
“The Architect of Beauty”
MIROS独自の美容成分PIKIÄ®（ピキア）※1は、
いわば「美のアーキテクト」。
肌を表面的に捉えるのではなく、
印象をかたちづくる構造そのものに着目しています。
分子デザイン発想※2に着目し、
自然界の膨大なタンパク質データをAIで解析し、
分子の立体配置や相互作用を設計図のように読み解くことで、
肌環境との整合性に配慮した精密な分子デザインを導き出しました。
この思想をもとに精密発酵技術を用い、
ヒト肌とアミノ酸配列が100%同一のマイクロ分子コラーゲン※3を創出。
PIKIÄ®※1は
肌の基礎構造※4に寄り添い、
整った印象を描くための中核となる存在です。
分子デザイン発想²
AI設計 x 精密発酵
AI Design
Through a molecular design approach, vast protein sequence data from nature is analyzed using AI to engineer precise molecular structures. Key performance functions are defined upfront, and candidates are screened through iterative simulations — enabling material innovation driven by efficacy and scalability, not chance.
Precision Fermentation
Guided by insights derived from AI design, fermentation conditions are precisely controlled to minimize molecular variability. This manufacturing technology enables the continuous production of materials defined by uniformity, stability, and uncompromising quality.
100% Skin-identical
Mirroring the amino acid sequence of type I collagen, PIKIÄ®¹
offers exceptional compatibility with the skin.
Micro-molecular
分子構造の均一性と設計精度に配慮したマイクロ分子設計。
素材としての整合性を重視し、なめらかに広がる使用感と、処方設計の自由度を支える構造を追求しています。
100% Vegan
Developed through precision fermentation without animal-derived ingredients, reflecting a commitment to clean and ethical formulation.
The Genesis: A Chance Meeting in New York
Headquartered in Germany, Cambrium develops next-generation materials using synthetic biology and AI-driven molecular imaging techniques. The company is backed by leading global investors, including Google’s AI-focused venture arm, and focuses on computational approaches to building bio-based materials.
A chance meeting in New York between Cambrium’s CEO, Mitchell Duffy, and MIROS founder Eita Nakagawa became the spark that led to the creation of MIROS and laid the foundation for its molecular design approach.
Mitchell Duffy (right), CEO of Cambrium
Eita Nakagawa (left), Founder of MIROS
BERLIN, GERMANY – OCT 2025
CONVERSATION
Eita - The cycles of regeneration inherent in the natural world have always been my primary source of inspiration. I am deeply grateful that my curiosity for science and my profound respect for nature have led me to collaborate with the world’s leading biotechnology team.
Mitchell - At Cambrium we use AI to design and build novel proteins.
We’re creating a new material world using nature’s building blocks.
We began by reimagining one of the most ancient and abundant proteins: collagen.
Eita - In skincare, collagen is essential. It gives our skin a youthful impression.
When I heard Cambrium designed a collagen identical to our own skin, I was instantly drawn in.
Mitchell - We built Cambrium to reimagine and transform industries, beginning with skincare.
Through MIROS, Eita is bringing this holistic vision to life.
Eita - I was inspired by timeless Japanese principles.
But what fascinates me is how this technology can unite something so deeply rooted in tradition, with the materials of the future.
Mitchell - Focusing on collagen—the most abundant protein in the extracellular matrix—we have successfully leveraged AI to decode the blueprints of molecular evolution spanning millions of years. Guided by these blueprints and powered by precision fermentation, we have created a 100% vegan, nano-sized collagen that possesses a sequence identical to that of human skin. This unique collagen has the power to restore and optimize the skin’s inherent condition.
未来の知が導く美しさへ
年齢やジェンダーを問わず、自分を慈しみ一日一日を大切に生きるすべての人へ。
バイオテクノロジーと日本の自然素材、発酵技術を活かした成分群を組み合わせて配合。
MIROSのすべてのスキンケアアイテムは,
PIKIÄ®※1を核に、サッカロミセス／コメ発酵液、ホワイトラベンダー、ユキノシタ、イロハモミジなどの国産植物エキスを丁寧に重ねました。